Gene name:
AZI2 (NAP1;TBKBP2) ;
Protein name:
5-azacytidine-induced protein 2 ;
Alternative:
TILP ;NF-kappa-B-activating kinase-associated protein 1 (Nak-associated protein 1) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with IKBKE, TBK1 and TICAM1.
Function:
Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MDALVEDDIC | ILNHEKAHKR | DTVTPVSIYS | GDESVASHFA | LVTAYEDIKK |
100:
RLKDSEKENS | LLKKRIRFLE | EKLIARFEEE | TSSVGREQVN | KAYHAYREVC |
150:
IDRDNLKSKL | DKMNKDNSES | LKVLNEQLQS | KEVELLQLRT | EVETQQVMRN |
200:
LNPPSSNWEV | EKLSCDLKIH | GLEQELELMR | KECSDLKIEL | QKAKQTDPYQ |
250:
EDNLKSRDLQ | KLSISSDNMQ | HAYWELKREM | SNLHLVTQVQ | AELLRKLKTS |
300:
TAIKKACAPV | GCSEDLGRDS | TKLHLMNFTA | TYTRHPPLLP | NGKALCHTTS |
350:
SPLPGDVKVL | SEKAILQSWT | DNERSIPNDG | TCFQEHSSYG | RNSLEDNSWV |
392:
FPSPPKSSET | AFGETKTKTL | PLPNLPPLHY | LDQHNQNCLY | KN
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rat
Mouse
ELISA Kit for Human 5-azacytidine-induced protein 2
ELISA Kit for Human 5-azacytidine-induced protein 2
ELISA Kit for Human 5-azacytidine-induced protein 2
ELISA Kit for Human 5-azacytidine-induced protein 2
CLIA Kit for Human 5-azacytidine-induced protein 2
CLIA Kit for Human 5-azacytidine-induced protein 2
CLIA Kit for Human 5-azacytidine-induced protein 2
CLIA Kit for Human 5-azacytidine-induced protein 2
Polyclonal Antibody for Human 5-azacytidine-induced protein 2
Polyclonal Antibody for Human 5-azacytidine-induced protein 2
Polyclonal Antibody for Human 5-azacytidine-induced protein 2
Polyclonal Antibody for Human 5-azacytidine-induced protein 2
Monoclonal Antibody for Human 5-azacytidine-induced protein 2
Monoclonal Antibody for Human 5-azacytidine-induced protein 2
Monoclonal Antibody for Human 5-azacytidine-induced protein 2
Monoclonal Antibody for Human 5-azacytidine-induced protein 2
Protein for Human 5-azacytidine-induced protein 2
Protein for Human 5-azacytidine-induced protein 2
Protein for Human 5-azacytidine-induced protein 2
Protein for Human 5-azacytidine-induced protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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"Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling."
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH TBK1 AND IKBKE;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORMS 1 AND 2)
3.
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Embryo .
tissue :
Hepatoma .
4.
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
Mural R.J.
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more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH TICAM1
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH IKBKE
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-353;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-353;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.
"Functional dissection of the TBK1 molecular network."
Goncalves A.
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PLoS ONE6:E23971-E23971(2011)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH TBK1