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Index > Protein center > AZI2(Gene name) > Human
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  • AZI2 (Gene name),
  • 5-azacytidine-induced protein 2 (Protein name ),  AZI2_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    AZI2(NAP1;TBKBP2);
    Protein name:
    5-azacytidine-induced protein 2;
    Alternative:
    TILP;NF-kappa-B-activating kinase-associated protein 1(Nak-associated protein 1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with IKBKE, TBK1 and TICAM1.
    Function:
    Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFN-beta promoter activation via TICAM1.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    392
    Sequence:
    50:
    MDALVEDDIC | ILNHEKAHKR | DTVTPVSIYS | GDESVASHFA | LVTAYEDIKK | 
    100:
    RLKDSEKENS | LLKKRIRFLE | EKLIARFEEE | TSSVGREQVN | KAYHAYREVC | 
    150:
    IDRDNLKSKL | DKMNKDNSES | LKVLNEQLQS | KEVELLQLRT | EVETQQVMRN | 
    200:
    LNPPSSNWEV | EKLSCDLKIH | GLEQELELMR | KECSDLKIEL | QKAKQTDPYQ | 
    250:
    EDNLKSRDLQ | KLSISSDNMQ | HAYWELKREM | SNLHLVTQVQ | AELLRKLKTS | 
    300:
    TAIKKACAPV | GCSEDLGRDS | TKLHLMNFTA | TYTRHPPLLP | NGKALCHTTS | 
    350:
    SPLPGDVKVL | SEKAILQSWT | DNERSIPNDG | TCFQEHSSYG | RNSLEDNSWV | 
    392:
    FPSPPKSSET | AFGETKTKTL | PLPNLPPLHY | LDQHNQNCLY | KN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    MIM:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human 5-azacytidine-induced protein 2
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    E14125h
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    ELISA Kit for Human 5-azacytidine-induced protein 2
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    ELISA Kit for Human 5-azacytidine-induced protein 2
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    ELISA Kit for Human 5-azacytidine-induced protein 2
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    CLIA Kit for Human 5-azacytidine-induced protein 2
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    CLIA Kit for Human 5-azacytidine-induced protein 2
    Cat.:
    U14125r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 5-azacytidine-induced protein 2
    Cat.:
    U14125h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 5-azacytidine-induced protein 2
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    U14125m
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    Packing:
    96T
    Polyclonal Antibody for Human 5-azacytidine-induced protein 2
    Polyclonal Antibody for Human 5-azacytidine-induced protein 2
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    P14125Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 5-azacytidine-induced protein 2
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    Polyclonal Antibody for Human 5-azacytidine-induced protein 2
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human 5-azacytidine-induced protein 2
    Monoclonal Antibody for Human 5-azacytidine-induced protein 2
    Monoclonal Antibody for Human 5-azacytidine-induced protein 2
    Monoclonal Antibody for Human 5-azacytidine-induced protein 2
    Protein for Human 5-azacytidine-induced protein 2
    Protein for Human 5-azacytidine-induced protein 2
    Protein for Human 5-azacytidine-induced protein 2
    Protein for Human 5-azacytidine-induced protein 2

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    References
    1. 1.
      "Identification of NAP1, a regulatory subunit of IkappaB kinase-related kinases that potentiates NF-kappaB signaling."
      Fujita F. , Taniguchi Y. , Kato T. , Narita Y. , Furuya A. , Ogawa T. , Sakurai H. , Joh T. , Itoh M. , Delhase M. , Karin M. , Nakanishi M.
      Mol. Cell. Biol.23:7780-7793(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH TBK1 AND IKBKE;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    2. 2.
      Inohara N. , Koseki T. , Nunez G.
      Submitted (1998-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORMS 1 AND 2)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Embryo.
      tissue: Hepatoma.
    4. 4.
      "The DNA sequence, annotation and analysis of human chromosome 3."
      Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
      Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "NF-kappaB-activating kinase-associated protein 1 participates in TLR3/Toll-IL-1 homology domain-containing adapter molecule-1-mediated IFN regulatory factor 3 activation."
      Sasai M. , Oshiumi H. , Matsumoto M. , Inoue N. , Fujita F. , Nakanishi M. , Seya T.
      J. Immunol.174:27-30(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TICAM1
    7. 7.
      "SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK."
      Ryzhakov G. , Randow F.
      EMBO J.26:3180-3190(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH IKBKE
    8. 8.
      "Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
      Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
      Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-353;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-353;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH TBK1
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